ESSENTIAL ROLE OF BRADIKININ IN THE COURSE OF BASIC LIFE PROCESSES

Kinins are polypeptides formed from α 2-globulins in blood plasma under the influence of the enzyme kallikrein (kallikrein-kinin system). Most famous of them are bradykinin and kallidin.

Bradykinin, as a member of the kinin group of proteins, is a physiologically and pharmacologically active peptide with vasodilatory properties. Due to its specific action, blood vessels expand and blood pressure drops. It is important to note that his actions are local in nature. This feature of the peptide is currently widely used in pharmacology for the treatment and prevention of heart failure and arterial hypertension.

With discovering of an increasing number of processes under the influence of bradykinin and related diseases, as well as due to the extreme relevance of the topic due to the COVID-19 pandemic, at the moment the topic needs extensive research.