Synthesis and antimicrobial screening of cyanopyridines

Department of Chemistry, Saurashtra University, Rajkot-360 005, India

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Manuscript received 3 May 2001, revised 5 November 2001, accepted 11 April 2002

2-Amino-3-cyano-4-(2'-chloro-7'-methylquinolin-3'-y1)-6-arylpyridines (3a-n) have been synthesized by the condensation of chalcones (2a-n) with malononitrile and ammonium acetate. All the compounds have been screened for their antimicrobial activity.