Syntheses, characterization and biological activities of two carbamate pesticides

Chemistry Department, D. S. College Aligarh-202 001, India

Manuscript received 4 August 2003, revised 12 April 2004. accepted 11 June 2004

                                                                                                                                                              \(SC_2H_5\)

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Two carbamate pesticides namely S-ethyl-N-[(methylcarbamoyl)oxy]thioacetimidatc (a) (CH₃-C=NOCONHCH₃) and N-phenyl-(ethylcarbamoyl)propyl carbamate (b) [C₆H₅NH-COO-CH(CH₃)-CO-NH-(C₃H₇)] were synthesized in the laboratory. With the help of elemental analysis. IR and NMR spectra their structures were elucidated. The biological studies showed that S-ethyl-N-[(methylcarbamoyl)oxy]thioacetimidate (a) acts as insecticide against insects causing damages to potato, tomato, cabbage plants, while N-phenyl-(ethylcarbamoyl)propyl carbamate (b) has herbicidal character and can be used for cabbage and legume family crops. For estimation of the toxicity of these pesticides LC₅₀ and LD₅₀ were determined. The results revealed that for fish and rats compound (a) was more toxic than compound (b).