Published January 5, 2022 | Version v1

Detection of neurofilament light chain with label-free electrolyte-gated organic field-effect transistors

  • 1. Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, Modena 41125, Italy
  • 2. Department of Biomedical, Metabolic and Neurosciences, University of Modena and Reggio Emilia, Via Campi 287, Modena 41125, Italy
  • 3. Department of Physics, Informatics and Mathematics, University of Modena and Reggio Emilia, Via Campi 213/a, Modena 41125, Italy

Description

The uploaded data include

i) transfer curves registered at every NF-L concentration;

ii) transfer curves for control experiments;

iii) raw AFM data acquired after electrode incubation in 0 M, 1 pM, 100 pM and 10 nM [NF-L].

Electrical measurements were acquired in 50 mM PBS, pH 7.4 under static conditions.

Anti-NF-L antibodies were immobilized on the gate electrode through cys-Protein G. The gate surface has been subsequently passivated through 11-mercaptoundecyl-triethylene glycol SAM.

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Additional details

Funding

European Commission
BORGES - Biosensing with ORGanic ElectronicS 813863