CoII and ZnII complexes of Schiff bases derived from fluoroaminothiazole spectral, magnetic and biological studies

School of Chemical Sciences, Solapur University, Solapur-413 255, Maharashtra, India
E-mail: anjanalawand@yahoo.co.in Fax: 91-217-2744770
Manuscript received 26 April 2010, revised 29 September 2010, accepted 05 October 2010

Co^II and Zn^II complexes of Schiff bases derived from 4-(p-Duorophenyl)-2-aminothiazole and o-hydroxyaldehydes {substituted salicylaldehyde, o-vanillin and 2-hydroxy-1-naphthaldehyde) have been synthesized. The complexes were characterized by elemental {C, H, N and metal) and spectral (UV-Visible and IR) analyses, magnetic susceptibility and conductivity measurements and evaluation of biological activities. The complexes possess 1 : 2 metal : ligand stoichiometry (ML₂) and an octahedral geometry. Various ligand field parameters (B, Dq, β, F₂ and F₄, F² and P, v₃/v₁, v₂/v₁, v₃/v₂ and Dq/B etc.) for Co^II complexes have been calculated. The complexes exhibit enhanced antibacterial and antifungal activity as compared to the parent ligands. This phenomenon is explained on the grounds of Overtone's concept and chelation theory.