Published May 11, 2017
| Version v1
Journal article
Open
MIRACLE OF NATURE GYMNEMA SYLVESTRE - A REVIEW
Authors/Creators
- 1. Department of Biological Sciences, Mahatma Gandhi Chirakoot Gramodaya Vishwavidyalaya, Chitrakoot Satna, Madhya Pradesh
Description
Higher plants are the source of a large number of chemicals with wide range of medicinal, pharmacological and insecticidal properties. In recent years there is a great demand for plant-based products because of the broad biological activities, safety without any toxic side effects and low impact on environment. Gymnema sylvestre (Family-Asclepiadaceae) is one of the important medicinal plants of India. Gymnema is popularly known as gurmar or Madhunashini for its remarkable property of temporally paralyzing the sensory perception of sweet. The active principle of the drug is widely used in indigenous medicine in the treatment of diabetes mellitus, complex mixture of gymnemic acids found in the leaves. Presently there is a vast market demand for this plant in national and international market. The present review describes the various morphological, medicinal, chemical, pharmacological activities and biotechnological aspects of Gymnema sylvestre.
Files
162.PDF
Additional details
References
- 1. Agnihotri A K, Khatoon S, Agarwal M, Rawat A S, Mehrotra S and Pushpangadan. Pharmacognostical evaluation of Gymnema sylves R. Br. Nat prod sci, 2004; 10(4):168-72. 2. Bishayee A and Chatterjee M. Hypolipidemic and antiatherosclerotic effects of Gymnema sylvestre leaf extract in albino rats fed on high fat diet. Phyt Res, 1994; 8(2): 118-20. 3. B. S. Sastry, Gymnema sylvestre, Bhav Prakash Nighantu, Chaukhambha, Varanasi, India, 1994. 4. B. Parimala Devi and R. Ramasubramaniaraja, "Pharmacognostical and antimicrobial screening of Gymnema sylvestre R.Br, and evaluation of Gurmar herbal tooth paste and powder, composed of Gymnema sylvestre R.Br, extracts in dental caries," International Journal of Pharma and Bio Sciences, vol. 1, no. 3, pp. 1–16, 2010 5. Chopra R N, Nayar S L and Chopra I C. Glossary of Indian Medicinal Plants; Supplement. Council of Scientific and Industrial Research, New Delhi, 1992; 319-22. 6. David Beverly C and Sudarsanam G. Antimicrobial activity of Gymnema sylvestre (Asclepiadaceae). Journal of Acute Disease, 2013; 2(3): 222-225. 7. Ekka N R and Dixit V K. Ethno-pharmacognostical studies of medicinal plants of Jashpur district (Chhattisgarh). International journal of Green Pharmacy, 2007; 1(1); 2-4. 8. Grijesh Kumar Mall, Pankaj Kishor Mishra and Veeru Prakash Antidiabetic and Hypolipidemic Activity of Gymnema sylvestre in Alloxan Induced Diabetic Rats Global Journal of Biotechnology & Biochemistry 4 (1): 37-42, 2009 ISSN 2078-466X 9. G. Kishor Naidu, K. Chandra Sekhar Naidu and B. Sujatha In Vitro Antibacterial Activity and Phytochemical Analysis of Leaves of Gymnema sylvestre Retz. R. Br. International Journal of PharmTech Research CODEN (USA): IJPRIF ISSN : 0974-4304 Vol.5, No.3, pp 1315-1320, July-Sept 2013 10. Jitender K M, Manvi F V, Nanjwade B K, Alagawadi K R and Sanjiv S. Immuno - modulatory activity of Gymnema sylvestre leaves extract on in vitro human neutrophils. J.Pharmacy Res, 2009; 2(8): 1284-1286. 11. Joseph ES, Gopal SR, Hugh MM, Smith RV, Massab HF and Cochran KW. Isolation and anti-viral activity of the Gymnemic acids. Specialia, Experientia, 1968; 15(3): 302-303. 12. Kiranmai M, Kazim SM and Ibrahim M. Combined wound healing activity of Gymnema sylvestre and Tagetes erecta Linn. Int. J. Pharmaceu. Appl, 2011; 2(2):135-140 13. Kalyani Singh, Bandita Deo Journal of Medicinal Plants Studies 2014; 2(4): 19-23 14. K. R. Kirtikar and B. D. Basu, Indian Medicinal Plants, vol. 3, Periodicals Experts, Delhi, India, 1975. 15. M. Surendra Kumar., N. Astalakshmi., Arshida. PT., Deepthi. K., Nidhin Devassia. M., Shafna. PM and G. Babu. World Journal of Pharmacy and Pharmaceutical Sciences, SJIF Impact Factor 5.210 .Volume 4, Issue 10, 430-448. Review Article ISSN 2278 – 4357. 16. Minal Wani, Faizan Ali Sarvar, Juhi Agrawal, Jyoti Deshpande,Siji Mathew, Madhukar Khetmalas Qualitative Phytochemical Analysis and antimicrobial activity studies of Gymnema sylvestre R. Br. Acta Biologica Indica 2012, 1(1):121-124 17. Malik JK, Manvi FV, Alagawadi KR and Noolvi M. Evaluation of anti-inflammatory activity of Gymnema sylvestre leaves extract in rats. Int J Green Pharm, 2008; 2(2):114-15. 18. M. Anis, M. P. Sharma, and M. Iqbal, "Herbal ethnomedicine of the Gwalior forest division in Madhya Pradesh, India," Pharmaceutical Biology, vol. 38, no. 4, pp. 241–253, 2000. 19. M. S. Akhtar and V. Bhakuni, "Streptococcus pneumoniae hyaluronate lyase: an overview," Current Science, vol. 86, no. 2, pp. 285–295, 2004 20. Nimisha verma, V.K. Shakya and R.C. Saxena Pest Control and Ayurvedic Drug Research Laboratory S.S.L. Jain P.G. College, Vidisha-464 001, India. 21. Ohmori R, Iwamoto T, Tago M, Takeo T, Unno T and Itakura H. Antioxidant activity of various teas against free radicals and LDL oxidation. Lipids, 2005; 40(8): 849-53. 22. Pratibha Gupta1 and Pratibha Singh Antimicrobial activity of Gymnemic acid on pathogens- Gymnema sylvestre R.Br international journal of current microbiology and applied science ISSN: 19-7706 Volume 3 Number 5 (2014) pp. 40-45 23. P. Marsh and M. Martin, Oral Microbiology, vol. 3, Chapman and Hall, London, UK, 1992. 24. Srikanth AV, Sayeeda M, Lakshmi NM, Ravikumar P and Madhava RB. Anticancer activity of Gymnema sylvestre R.Br. Int. J. Pharmaceu. Sci. Nanotech, 2010; 3(1):87-899. 25. Walter BM, Maria CDN, Bettina MRP and Nuno AP. Plant natural products active against snake-bite-the molecular approach. Phytochemistry, 2000; 55: 627-642. 26. Kritikar K and Basu B. Indian medicinal plants. Dehradun: International book distributors, 1998; 1625. 27. Mohsina Syedy and Krishnendra Singh Nama international journal of pure & applied bioscience (6): 318-325 (2014) ISSN: 2320 – 7051 28. Mohsina Syedy and Krishnendra Singh Nama. Gymnema sylvestre: A miracle fruit for Diabetes cure. International Journal of pure and applied bioscience, 2014; 2(6): 318-325. 29. Nadkarni KM. Indian Materia Medica. Popular prakashan, Bombay, 1993; 596-599. 30. Selvanayagam ZE, Gnanavendhan SG, Chandhra Shekaran P, Balakrishna K and Rao RB. Plants with antisnake venom activity- a review on pharmacological and clinical studies. Fitoterapia, 1995; 65: 99-11. 31. Subramaniyan Vijayakumar and Srinivasan Prabhu. Gymnema sylvestre – A Key for Diabetes Management – A Review. Pharmacology & Toxicology Research, 2014; 1(1):1-10. 32. Vaidyaratnam P. Indian Medicinal Plants. Orient Longman Publisher, Madras, 1995; 107-9.