Microwave-mediated synthesis of 3-unsubstituted β-lactams with aqueous trimethylborane

Department of Chemistry, Faculty of Engineering & Technology, Veer Bahadur Singh Purvanchal University,

Jaunpur-222 003, Uttar Pradesh, India

Department of Chemistry, University of Texas-Pan American,1201 W. University Dr., Edinburg, TX 78539, USA

The University of Texas M. D. Anderson Cancer Center, Department of Molecular Pathology, 1515 Holcombe Blvd,

Houston, TX 77030, USA

Current Address: Community Health System of South Texas, 3135 South Sugar Road, Edinburg, TX 78539, USA

E-mail: bimalbanik10@gmail.com, bimal.banik@chsst.org

Manuscript received 03 October 2018, accepted 01 November 2018

A new microwave-induced method for the preparation of 3-unsubstituted β-lactams is explored via aqueous trimethylboranemediated reaction of the corresponding xanthates.