Green Synthesis Of Reduced Graphene Oxide Nanoparticles, Its Characterization and Antimicrobial Properties against Common Oral Pathogens

The graphene and its based materials are widely used in biomedical applications especially in oseointegration and implants preparation. We synthesized the reduced graphene oxide nanoparticles by green synthesis method. The plant extract of Andrographis paniculata and Ocimum sanctum Linn were used as reducing agent. UV-vis spectroscopy, FT-IR, XRD, TEM analysis were used for characterization of the resulting nanoparticles. The antimicrobial activity of the nanoparticles was also assessed against common oral pathogens. Brine Shrimp Lethality assay was utilized to check the cytotoxicity of newly synthesized nanoparticles. The nanoparticles were successfully synthesized and showed good antimicrobial activity with minimum cytotoxic effects.