Published October 1, 2021 | Version 1.0
Project deliverable Open

Guidance on the GRACIOUS Framework for grouping and read-across of nanomaterials and nanoforms


  • 1. Yordas Group


The GRACIOUS project has developed a highly innovative science-based framework that supports the assessment of risk posed by the ever increasing array of nanomaterials on the market and under development. The Framework streamlines the process for assessing their risk by logically grouping nanomaterials thereby allowing extrapolation between (read-across) nanomaterials and reducing the need to assess exposure to and toxicity on a case by case basis.

The Guidance Document introduces a new user of the Framework to the essential steps they will need to take to use the Framework to support their grouping and read-across decisions and uses worked examples to show how these steps have been done practically in the GRACIOUS project.


GRACIOUS Framework Guidance FINAL 22 NOV 21.pdf

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GRACIOUS – GRACIOUS: Grouping, Read-Across, CharacterIsation and classificatiOn framework for regUlatory risk assessment of manufactured nanomaterials and Safer design of nano-enabled products 760840
European Commission