Published September 24, 2021 | Version v1
Dataset Open

Annotation results of two human retina organoids

Authors/Creators

  • 1. Helmholtz Centre for Environmental Research GmbH - UFZ

Description

Cell annotation was based on i) marker genes which were extracted from literature and expert knowledge, or (ii) via a transfer learning tool CaSTLe (Lieberman Y, Rokach L, Shay T, 2018) using the Cowan et al. (2020) organoid reference data set.

Data preprocessing of both scRNA-seq data sets was done in scanpy (Wolf, F., Angerer, P. & Theis, 2018), and are included as h5ad-files.

The annotation results are included in the .csv files

Files

Chapter9_CaSTLe_Annot_HRO2.csv

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Additional details

References

  • Cowan, C. S. et al. (2020). Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution. Cell , 182, 1623–1640.e34.