Published February 19, 2021
| Version 2.0.0
Dataset
Open
Aminophylline induces two types of arrhythmic events in human pluripotent stem cell-derived cardiomyocytes - Dataset
Authors/Creators
- 1. CEITEC, Masaryk University, Brno, Czech Republic;
- 2. Department of Respiratory Diseases, Faculty of Medicine, Masaryk University, University Hospital Brno, Czech Republic; Faculty of Medicine, Masaryk University, Brno, Czech Republic;
- 3. Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic; First Department of Internal Medicine – Cardioangiology, Faculty of Medicine, Masaryk University and St. Anne's University Hospital, Brno, Czech Republic
- 4. Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic;
- 5. Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic;
- 6. Faculty of Medicine, Masaryk University, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic; First Department of Internal Medicine – Cardioangiology, Faculty of Medicine, Masaryk University, St. Anne's University Hospital, Brno, Czech Republic
- 7. Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
- 8. Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital, Brno, Czech Republic;
- 9. Department of Respiratory Diseases, Faculty of Medicine, Masaryk University, University Hospital Brno, Czech Republic
Description
This dataset contains raw and processed AFM data of measuring contractility activity of 3D clusters of cardiomyocytes (Embryoid bodies) after administrating bronchodilator Aminophylline in increasing concentration. Dataset will be in future coupled with journal article:''Aminophylline induces two types of arrhythmic events in human pluripotent stem cell-derived cardiomyocytes''.
2.0.0 - Changelog
-Addition of results of HL-1 cells measurement including a multielectrode array (MEA) and Calcium sparklings measurements.
-Removing of Barium measurements data
Notes
Funding:
This work was supported by the Ministry of Health of the Czech Republic, grant nr. NU20-06-00156.
Acknowledgments:
CIISB, Instruct-CZ Centre of Instruct-ERIC EU consortium, funded by MEYS CR infrastructure project LM2018127, is gratefully acknowledged for the financial support of the measurements at the CF Nanobiotechnology.