Published August 1, 2021 | Version 1.0
Dataset Open

Risk factors for treatment failure in women with uncomplicated lower urinary tract infection

  • 1. University of Geneva Hospitals and Faculty of Medicine
  • 2. the Medical University of Lodz
  • 3. Family Doctors ' Clinic Pomorska96
  • 4. Sackler Faculty of Medicine
  • 5. Rabin Medical Center

Description

Origin :

This dataset represent a sub-population of a previous clinical trial. 

Huttner A, Kowalczyk A, Harbarth S, et al.. Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women: A Randomized Clinical Trial. JAMA. 2018;319(17):1781-1789. DOI: 10.1001/jama.2018.3627.

 

Databases : 

  • 1st database : women included in the nested cohort study (n=350)
  • 2nd database : women with microbiologically conformed UTI (n=279)
  • 3d database : women with E.coli related UTI (n=185)

Important : 

  • Data from Tel Aviv have been removed from this dataset, and might be shared by the corresponding author upon reasonable request at the following address (romainmartischang@gmail.com).

Codebook : 

  • v1_XXX; 0/1 : All symptoms present at baseline
  • v1dipstick : Negative (0), nitrites (1), leukocytes esterase (2), both (3), not done (4)
  • centre : recruitment centre (CHE or POL)
  • rfscore : risk factor for carrying a resistant bacteria as defined in the initial trial
  • treatment : nitrofurantoin (0) vs fosfomycin (1)
  • dm : diabetes mellitus 
  • case2 : bacteriological failure at 28 days as defined in the initial trial
  • case1 : clinical failure at 28 days as defined in the initial trial
  • recur14 : bacteriological failure at 14 days as defined in the initial trial
  • fail14 : clinical failure at 14 days as defined in the initial trial
  • v1pathogen[1-3] : pathogen present at baseline

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