Database in the article titled Krüppel-like factor 5 mediates beta-secretase expression and involves in pathogenesis of Alzheimer's disease
Authors/Creators
- 1. Clinical Laboratory of Xuanwu Hospital, Capital Medical University
Description
Fig2c. Representative Western blots of KLF5 (upper panel) and BACE1 (middle panel) protein expression in the cerebral cortex of APP/PS1 mice and WT mice.
Fig2e. Representative Western blots of KLF5 (upper panel) and BACE1 (middle panel) protein expression in the hippocampus of APP/PS1 mice and WT mice.
Fig2i. Expression and sublocalization of KLF5 and BACE1 in the brain of APP/PS1 mice and WT mice by immunofluorescence laser confocal microscopy.
Fig3b1. Representative Western blots and relative quantification of KLF5 and BACE1 protein expression in HT22 cells transfected with KLF5 or vector.
Fig3e1. Representative Western blots and relative quantification of KLF5 and BACE1 protein expression in HT22 cells transfected with KLF5 shRNA or control shRNA.
Fig3g. Representative Western blots of APP (upper panel) and KLF5 (middle panel) protein expression in the HT22 cells co-transfected with APPswe and KLF5 or control vector.
Fig3h. Representative Western blots and relative quantification of APP-CTFβ protein expression in HT22 cells co-transfected with APPswe and KLF5 or control vector.
Fig5a. Representative Western blots and relative quantification of BACE1 protein in HT22 cells co-transfected with BACE1-shRNA or control-shRNA and KLF5 or control vector.
Fig5c. Representative Western blots and relative quantification of APP-CTFβ protein in HT22 cells co-transfected with BACE1-shRNA or control-shRNA and KLF5 or control vector.
Fig6e. Representative Western blots and relative quantification of KLF5 and BACE1 protein expression in the cerebral cortex of different group of mice.
Fig6f. Representative Western blots and relative quantification of KLF5 and BACE1 protein expression in the hippocampus of different group of mice.
Fig6g. Expression of KLF5 and BACE1 in the brain of different group of mice by immunofluorescence (×200).
Fig6j. Staining of amyloid plaques in the brain of different group of mice. k The level of Aβ40 and Aβ42 in the brain of different group of mice.
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