CCLE

CCLE PharmacoSet (PSet) generated by ORCESTRA. Metadata can be found on ORCESTRA at: http://orcestra.ca/10.5281/zenodo.4721823

Disclaimer

The CCLE data were generated and shared by the Broad Institute of Harvard and MIT as part of the Cancer Cell Line Encyclopedia project. The Haibe-Kains Lab has reprocessed and re-annotated the data to maximize overlap with other pharmacogenomic datasets.

Data Usage Policy

CCLE publishes its data under the Terms and Conditions linked here. The DepMap data, including the CCLE data, are provided under Creative Commons Attribution 4.0 license.

Contact depmap@broadinstitute.org for more information

Please cite the following when using these data

Cancer Cell Line Encyclopedia Consortium, and Genomics of Drug Sensitivity in Cancer Consortium. 2015. Pharmacogenomic Agreement between Two Cancer Cell Line Data Sets. Nature 528 (7580):84–87. https://doi.org/10.1038/nature15736.

Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, William R. Sellers, Robert Schlegel, Levi A. Garraway, et. al. 2012. The Cancer Cell Line Encyclopedia Enables Predictive Modelling of Anticancer Drug Sensitivity. Nature 483 (7391):603–7. https://doi.org/10.1038/nature11003.

For omics data: 

Mahmoud Ghandi, Franklin W. Huang, Judit Jané-Valbuena, Gregory V. Kryukov, ... Todd R. Golub, Levi A. Garraway & William R. Sellers. 2019. Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature 569, 503–508 (2019).

For metabolomics:

Haoxin Li, Shaoyang Ning, Mahmoud Ghandi, Gregory V. Kryukov, Shuba Gopal, ... Levi A. Garraway & William R. Sellers. The landscape of cancer cell line metabolism. Nature Medicine 25, 850-860 (2019).