Published April 4, 2021
| Version v1
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High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology
Authors/Creators
- 1. Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark
- 2. Nanion Technologies GmbH, Munich, Germany
- 3. Department of Pharmaceutical Chemistry & Bioanalytics, Institute of Pharmacy, Charles Tanford Protein Center, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany
Description
Contains a read_me file and data related to the publication: High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology
Notes
Søren Friis is a full-time employee of Nanion Technologies. The other authors declare no competing interests.
We acknowledge the Lundbeck Foundation (R139-2012-12390 to SAP and R218-2016-1490 to NB), the Boehringer Ingelheim Fond (to NB) and the University of Copenhagen for financial support.
Files
Compiled example current traces of variants tested in the APC screen, truncation constructs, SSD curves.pdf
Files
(18.1 MB)
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Additional details
Related works
- Is supplement to
- Preprint: 10.1101/2020.11.24.392498 (DOI)