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Published March 18, 2021 | Version v1
Dataset Open

hg19 syntenic ages

  • 1. Vanderbilt University
  • 2. University of California San Francisco

Description

# Hg19 46-way vertebrate tree syntenic block age files. 

Information for hg19 46-way vertebrate multiple sequence alignment can be found here - http://hgdownload.cse.ucsc.edu/goldenPath/hg19/multiz46way/README.txt

 

# Scripts generating these files

(1) Creating syntenic block .bed files

https://github.com/slifong08/enh_ages/blob/54084ff12e521c20cc5288d6cb3590fac93c11ed/age_arch/manuscript_scripts/get_spec_count_msa-hg19.py

(2) Assigning most recent common ancestor (MRCA) and patristic distances to syntenic blocks

https://github.com/slifong08/enh_ages/blob/54084ff12e521c20cc5288d6cb3590fac93c11ed/age_arch/manuscript_scripts/get_synteny_age_hg19.py


### Bed file
 

# File columns

["chr", "start", "end", "strand",  "reference_genome", "species_count", "length_synteny_block", "max_mrca",  "max_patr"]

# Definitions

"max_mrca" = the phylogenetic distance from Homo sapiens to the most recent common ancestor of the oldest taxon. 

"max_patr" = the phylogenetic distance from Homo sapiens to the oldest taxon.

"species_count" = the number of species' genomes the syntenic block maps to.

Files

Files (354.8 MB)

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