Published March 19, 2020
| Version v1
Poster
Open
Drug targeting in cancer therapy
Authors/Creators
- 1. Gymnasium der Kreuzschwestern, Ort/Gmunden, Austria
- 2. Dept. Biosciences, University of Salzburg, Austria
- 3. Sciencetainment, Ostermiething, Austria
Description
Drug targeting enables the local release of medication at the desired site or organ. This ensures that the drug asserts its effects focused to a small site, minimising systematic side effects. Drug targeting has been successfully applied in cancer therapy and can be performed actively or passively. During passive drug targeting, carriers containing the active cancer drug concentrate within the tumour tissue due to increased blood circulation and vascular permeation (enhanced penetration retention principle). Active drug targeting on the other hand, facilitates ligand-receptor interactions.
Files
22596-59458-1-SM.pdf
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