Published January 19, 2021 | Version v1

Behavioral and ephys data of research paper: Microsecond interaural time difference discrimination restored by cochlear implants after neonatal deafness

  • 1. University Medical Center Freiburg
  • 2. City University of Hong Kong

Description

The uploaded raw behavioral and electrophysiological data form the basis for our research study on "Microsecond Interaural Time Difference Discrimination Restored by Cochlear Implants After Neonatal Deafness". Based on this data we were able to show that neonatally deafened (ND) rats provided with precisely synchronized cochlear implant stimulation in adulthood can be trained to lateralize interaural time differences (ITDs) with essentially normal behavioral thresholds near 50 μs. Furthermore, comparable ND rats show high physiological sensitivity to ITDs immediately after binaural implantation in adulthood.

In addition to the raw data, we provided scripts to analyze the psychometric functions for the ITD sensitivity of our acoustically or electrically stimulated rats (see Fig. 1 of the manuscript). To reproduce the analysis of the electrophysiological data (see Figs. 3+4 of the manuscript), various analysis scripts were added in addition to the raw data. For a detailed description of the data analysis of these data, see section "Data analysis" of the Methods section of our manuscript.

 

Notes

Funding provided by: Deutscher Akademischer Austauschdienst (DAAD): Nicole Rosskothen-Kuhl, P.R.I.M.E. - Postdoctoral Researchers International Mobility Experience*
Crossref Funder Registry ID:
Award Number: REA grant agreement n 605728

Funding provided by: Hong Kong General Research Fund*
Crossref Funder Registry ID:
Award Number: 11100219

Funding provided by: Hong Kong Medical Research Fund *
Crossref Funder Registry ID:
Award Number: 06172296

Funding provided by: Shenzhen Science and Innovation Fund*
Crossref Funder Registry ID:
Award Number: JCYJ20180307124024360

Funding provided by: Baden-Wuerttemberg Ministry of Science*
Crossref Funder Registry ID:
Award Number: Research and Art and the University of Freiburg in the funding programme Open Access Publishing.

Funding provided by: Hong Kong General Research Fund
Crossref Funder Registry ID:
Award Number: 11100219

Funding provided by: Hong Kong Medical Research Fund
Crossref Funder Registry ID:
Award Number: 6172296

Funding provided by: Shenzhen Science and Innovation Fund
Crossref Funder Registry ID:
Award Number: JCYJ20180307124024360

Funding provided by: Baden-Wuerttemberg Ministry of Science
Crossref Funder Registry ID:
Award Number: Research and Art and the University of Freiburg in the funding programme Open Access Publishing.

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AcuteCI_ITDsingleClickExperimentsForAnalysis.csv

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Additional details

Related works

Is cited by
10.1101/498105 (DOI)