Published January 13, 2021 | Version v1

Different types of kinase inhibitors with experimentally confirmed mechanism of action

  • 1. Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Friedrich-Hirzebruch-Allee 6, D-53115 Bonn, Germany

Description

A data set of ATP-competitive and allosteric inhibitors of human protein kinases with mechanisms of action confirmed by X-ray crystallography is provided. Data were acquired from the Protein Data Bank (PDB) and the  KLIFS, ProfKin, ASD, and ChEMBL databases, curated, and organized. The composition of the data set is detailed in the accompanying readme.txt file.

 

 

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