Published January 24, 2019 | Version v1
Journal article Open

Nitric oxide protects against AKI by reprogramming metabolism

  • 1. Laboratory of Nephrology, Service of internal medicine specialties, Geneva University Hospitals, Geneva, Switzerland


New findings demonstrate that endothelial nitric oxide synthase regulates major metabolic pathways in the kidney proximal tubule, which confers protection against oxidative stress during acute kidney injury (AKI). These findings give new insights into AKI pathophysiology and nitric oxide biology , and identify new targets for the treatment of AKI.


NO Nature Review Immunology.pdf

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