Technology Assessment of Next Generation Sequencing in Personalized Oncology - TANGO Project
Published November 24, 2020 | Version V1
Dataset Open

Digitized patient level time to event data of overall survival

Creators

  • 1. Maastricht university medical centre+, Care and public health research institute (CAPHRI)
  • 2. Maastricht university medical centre+
  • 3. Erasmus medical centre
  • 4. Netherlands cancer institute-Antoni van Leeuwenhoek hospital, University of Twente

Description

This dataset contains digitized patient level time to event data for overall survival of patients with locally advanced and metastatic (stage IIIB/IV) Non-small cell lung cancer (NSCLC). The data can be used to recreate the original Kaplan-Meier survival curves that were published in randomized controlled trials, in order to perform secondary analysis on the survival data. In order to recreate a survival curve, you need two csv.files per trial arm that are in this 
database: (1) starting with 'surv_', containing the individual patient level time to event data, and (2) starting with 'natrisk_', containing the corresponding numbers at risk table. For the methodology and r-code that can be used for this purpose we refer to article that is linked to this dataset. 

Notes

The "Technology Assessment of Next Generation Sequencing in Personalized Oncology" (TANGO) project is funded by the ZonMw Personalised Medicine Programme under Dossier number: 846001002 in collaboration with KWF and Zilveren Kruis. The project period is 31 December 2016 – 31 May 2021.

Files

ALK_control_OS.zip

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Additional details

Related works

References
Journal article: 10.1016/j.critrevonc.2020.103035 (DOI)