Published July 6, 2020 | Version v3
Dataset Open

Preprocessed and Harmonised Transcriptomics Datasets for Psoriasis and Atopic Dermatitis

  • 1. Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland
  • 2. ITTM - Information Technology for Translational Medicine, Esch-sur-Alzette, Luxembourg

Description

The datasets uploaded within this record contain transcriptomics data of psoriasis and atopic dermatitis patients retrieved from the NCBI Gene Expression Omnibus and EBI ArrayExpress repositories. Overall, we retrieved 39 transcriptomics datasets, produced through both DNA microarrays and RNA-Sequencing technologies, along with relative meta-data tables. After data collection, each dataset was quality checked and preprocessed in order to obtain a harmonised source of data, ready-to-use for the research community. Beside, a thorough quality check was carried out on the retrieved meta-data, and data dictionaries were created (both for DNA microarry and RNA-Seq datasets) in order to homogenise the phenotypic data, enabling the comparability across the datasets. 

Files

PSO_and_AD_zenodo_upload_revised.zip

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Additional details

Funding

BIOMAP – Biomarkers in Atopic Dermatitis and Psoriasis 821511
European Commission

References

  • Federico, A., Hautanen, V., Christian, N. et al. Manually curated and harmonised transcriptomics datasets of psoriasis and atopic dermatitis patients. Sci Data 7, 343 (2020). https://doi.org/10.1038/s41597-020-00696-8