Data from: Metabolomics - Emory Cardiovascular Biobank

This DATSETNAMEreadme.txt file was generated on 2020-08-20 by ANURAG MEHTA and CHANG LIU

GENERAL INFORMATION

1. Title of Dataset: Emory Cardiovascular Biobank Metabolomics 

2. Author Information
    A. Principal Investigator Contact Information
        Name: Arshed A. Quyyumi, MD
        Institution: Emory University School of Medicine
        Address: 1462 Clifton Road NE, Suite 507, Atlanta, Georgia 30329
        Email: aquyyum@emory.edu

    B. Associate or Co-investigator Contact Information
        Name: Anurag Mehta, MD
        Institution: Emory University School of Medicine
        Address: 1462 Clifton Road NE, Suite 513, Atlanta, Georgia 30329
        Email: anurag.mehta@emory.edu

    C. Alternate Contact Information
        Name: Chang Liu
        Institution: Emory University School of Medicine
        Address: 1462 Clifton Road NE, Atlanta, Georgia 30329
        Email: chang.liu2@emory.edu

3. Date of data collection: 2004 to 2016

4. Information about funding sources that supported the collection of the data: National Heart, Lung, and Blood Institute grant 1P20HL113451

SHARING/ACCESS INFORMATION
 
1. Links to publications that cite or use the data: https://doi.org/10.1371/journal.pone.0237579

2. Links to other publicly accessible locations of the data: https://doi.org/10.5061/dryad.866t1g1mt

3. Links/relationships to ancillary data sets: none

4. Was data derived from another source? no

5. Recommended citation for this dataset: Mehta A, Liu C, Quyyumi AA. Emory Cardiovascular Biobank Metabolomics. 2020

DATA & FILE OVERVIEW

1. File List: Analysis_data_first_cohort.csv; Analysis_data_second_cohort.csv

2. Relationship between files: data of two separate cohorts

3. Additional related data collected that was not included in the current data package: none

4. Are there multiple versions of the dataset? no

METHODOLOGICAL INFORMATION: please see description in materials and methods section of the manuscript

DATA-SPECIFIC INFORMATION FOR: Analysis_data_first_cohort.csv

1. Number of variables: 6796

2. Number of cases/rows: 454

3. Variable List: 
GENEID: subject IDs
timetodeath3yr: time to death event or censoring at three years
death3yr: death event at three years
age: age in years
male: male gender, 1=male, 0=female
BlackRace: black race, 1=black, 0=non-black
batch: batch of metabolomics profiling
Strokehx: history of stroke, 1=yes, 0=no
CABGhx: prior CABG, 1=yes, 0=no
PVDhx: peripheral artery disease, 1=yes, 0=no
eGFR_max120_lt60: estimated glomerular filtration rate less than 60 ml/min/1.73m2, 1=yes, 0=no
curr_smoking: current smoking, 1=yes, 0=no
HFhx: heart failure history, 1=yes, 0=no
HTN: hypertension, 1=yes, 0=no
DM: diabetes, 1=yes, 0=no
mzXX_tXX: intensities of metabolic features

4. Missing data codes: NA

DATA-SPECIFIC INFORMATION FOR: Analysis_data_second_cohort.csv

1. Number of variables: 8729

2. Number of cases/rows: 322

3. Variable List: 
GENEID: subject IDs
timetodeath3yr: time to death event or censoring at three years
death3yr: death event at three years, 1=yes, 0=no
age: age in years
male: male gender, 1=male, 0=female
BlackRace: black race, 1=black, 0=non-black
batch: batch of metabolomics profiling
Strokehx: history of stroke, 1=yes, 0=no
CABGhx: prior CABG, 1=yes, 0=no
PVDhx: peripheral artery disease, 1=yes, 0=no
eGFR_max120_lt60: estimated glomerular filtration rate less than 60 ml/min/1.73m2, 1=yes, 0=no
curr_smoking: current smoking, 1=yes, 0=no
HFhx: heart failure history, 1=yes, 0=no
HTN: hypertension, 1=yes, 0=no
DM: diabetes, 1=yes, 0=no
mzXX_tXX: intensities of metabolic features

4. Missing data codes: NA

Funding provided by: National Heart, Lung, and Blood Institute
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000050
Award Number: 1P20HL113451

Funding provided by: American Heart Association
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000968
Award Number: 19POST34400057