Published June 19, 2020 | Version 1.1.0
Dataset Open

Simultaneous three-dimensional vascular and tubular imaging of whole mouse kidneys with X-ray µCT

  • 1. Institute of Physiology, University of Zurich, Zurich, Switzerland
  • 2. Department of Chemistry, University of Zurich, Switzerland
  • 3. Laboratory for Animal Model Pathology (LAMP), Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Switzerland
  • 4. Electron Microscopy Unit, Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Switzerland
  • 5. Biomaterials Science Center, Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland

Description

µCT dataset of a mouse kidney injected with contrast agent XlinCA and scanned with 3.3 µm voxel size. Detailed sample preparation and image acquisition protocols are published as "Simultaneous three-dimensional vascular and tubular imaging of whole mouse kidneys with X-ray µCT" in Microscopy and Microanalysis.

Segmentations of the vascular and tubular lumina along with the renal tissue are provided as masks. The three different segmented features were combined into a single dataset and encoded as different gray values:

0: Background
51: Tubules
204: Tissue
255: Blood vessels

The Supplemental Video features a computer graphics visualization of the segmented masks. Blood vessel lumina are rendered in red, tissue in transparent blue and tubular lumina in yellow.

Files

Data_Kidney_X-ray_micro-CT.zip

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Additional details

Related works

Is documented by
Journal article: 10.1017/S1431927620001725 (DOI)

Funding

Swiss National Science Foundation
HR-Kidney - High Resolution 3D Functional Anatomy Database of the Kidney 205321_153523
Swiss National Science Foundation
NCCR Kidney.CH: Kidney Control of Homeostasis (phase II) 51NF40-158771