TCGA Chemotherapy Response Dataset

Dataset on chemotherapeutic drug responses in TCGA cancer patients, cross-referenced for a hit in TCIA.at database, consisting of clinical (TCGA), cancer tissue gene-expression (TCGA) and tumor-immunome (TCIA) features. The dataset consists of 5 common chemotherapy agents, 3 CRC agents (FOLFOX, 5FU, Oxaliplatin) and 2 Lung agents (Carboplatin, Cisplatin). FOLFOX as a combinational therapy or regimen, was compiled from timings of monotherapies given to patients and as such is a novel dataset derived from TCGA data. FOLFOX dataset is primarily firstline treatment, while other drugs are not to be interpreted as firstline treatments. Drug datasets are individually available in own CSV files.

Citation
Dalibor Hrg, Balthasar Huber, Lukas A. Huber. (2020). TCGA Chemotherapy Response Dataset. Zenodo. http://doi.org/10.5281/zenodo.3719291

The results here are in whole or part based upon data generated by the TCGA Research Network: https://www.cancer.gov/tcga.

License 
CC BY-SA 4.0 International https://creativecommons.org/licenses/by-sa/4.0. Authors take no liability for any use of this data.

Contributions
D. Hrg and B. Huber acknowledge major and equal work effort: data understanding, data science and dataset preparation (monotherapies and FOLFOX); L. A. Huber: help with dictionary of drug names and curration/cleaning of FOLFOX entries, clinical validation.

Contact & Maintenance
dalibor.hrg@gmail.com
dalibor.hrg@i-med.ac.at