Supplementary Material for "Efficient biocatalytic synthesis of dihalogenated purine nucleoside analogues applying thermodynamic calculations"

This is the supplementary material for our publication "Efficient biocatalytic synthesis of dihalogenated purine nucleoside analogues applying thermodynamic calculations". We wish to thank all authors for their contribution and have uploaded this dataset in their name.

We apologize that these files are not publicly available. Please contact Dr. Anke Kurreck for access to raw and analyzed data.

Naturally, this work builds on previous publications. Specifically, we have borrowed data from our recent work on the thermodynamic control of nucleoside phosphorolysis (10.1002/adsc.201901230; the full dataset can be found at 10.5281/zenodo.3568858) and employed equations and methodology described in our piece on yield optimization of nucleoside transgylcosylations (10.1002/cbic.201900740; the external supplementary information can be accessed at 10.5281/zenodo.3565561 and 10.5281/zenodo.3522588).