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Published December 10, 2019 | Version 0.1.1

alignparse: A Python package for parsing complex features from high-throughput long-read sequencing

  • 1. Fred Hutchinson Cancer Research Institute; University of Washington
  • 2. Fred Hutchinson Cancer Research Center; Howard Hughes Medical Institute

Description

alignparse is a Python package written by the Bloom lab. It is designed to align long sequencing reads (such as those from PacBio circular consensus sequencing) to targets, filter these alignments based on user-provided specifications, and parse out user-defined sequence features. For each read that passes the filters, information about the features (e.g. accuracy, sequence, mutations) is retained for further analyses.

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