Published November 30, 2015
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Supplementary Material: Conformational Ensemble of the Poliovirus 3CD Precursor Observed by MD Simulations and Confirmed by SAXS: A Strategy to Expand the Viral Proteome?
- 1. Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA
- 2. Department of Biochemistry and Molecular Biology, St Louis University School of Medicine, 1100 South Grand Ave, St Louis, MO 63104, USA
- 3. Huck Institutes of life sciences, The Pennsylvania State University, University Park, PA 16802, USA
Description
Supplementary video for Viruses 2015, 7(11), 5962-5986; doi:10.3390/v7112919; http://www.mdpi.com/1999-4915/7/11/2919.
Movie S1. Dynamic interface between 3C and 3D domains revealed by accelerated MD. The 3C and 3D domains are colored cyan and blue, respectively. The active-site residues of the protease (His-40, Glu-71, Cys-147) and the polymerase (Asp-416, Asp-511, Asp-512) domains are represented by red spheres to help identifying the relative orientations of two domains.
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viruses-88963-supplementary.zip
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- Is supplement to
- 10.3390/v7112919 (DOI)