Published June 11, 2019 | Version v1
Dataset Open

Suspect Lists for Neurotoxicant Screening

  • 1. LCSB, Uni Luxembourg
  • 2. US EPA / Leidos
  • 3. US EPA

Description

A range of lists for performing suspect screening of neurotoxicants, described in Table 1 of Schymanski et al (under revision), as well as the source data for the NEUROTOXINS list.

DNTEFFECTS (96): Chemicals with data demonstrating effects on neurodevelopment

DNTINVIVO (33): A (non-exhaustive) list of compounds documented to trigger developmental neurotoxicity (DNT) in at least two different laboratories

DNTPOTNEG (41): Suggested potential negative controls for developmental neurotoxicity (DNT) assays. Statins can also be used, see https://comptox.epa.gov/dashboard/chemical_lists/statins

HUMANNEUROTOX (190): A set of chemicals identified as potential neurotoxicants by the authors using literature, not necessarily active neurotoxicants.

NEUROTOXINS (511): A list of chemicals reported as neurotoxicants, compiled from public resources (see source file included here)

LITMINEDNEURO (1243): Chemicals associated with neurotoxicity compiled through systematic literature mining of PubMed using MeSH terms (node C10, subheadings “chemically induced”, “toxicity”, “poisoning”, or “adverse effects”) and associating these with single chemical substances.

Notes

Further details in manuscript currently under revision.

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