Intestinal microflora and nanomedicines (Review)

With age of humans is changing species composition of bacteria in the gut . Numerous studies have shown that with age there is a reduction of the number of viable bacteria of the genus Bacteroides and increasing of proteolytic bacteria such as Fusobacterium, Propionibacterium and Clostridium, in the intestines of older people, may indicate a tendency to putrefaction of colon, mainly in gut of patients undergoing antibiotic therapy. Studies have shown that in elderly patients have a place increasing of clostridia in combination with a significant increase in species diversity , especially after antibiotic therapy . Recently, the medical practice is to apply the new generation of drugs such as nanomedicines. Nanomedicines can be used orally and intravenously . As result of oral use is a negative effect on the intestinal microflora and, especially in the elderly.