Published September 18, 2018 | Version v1

Nanomaterial safety data integration with eNanoMapper database

  • 1. Ideaconsult Ltd., Sofia, Bulgaria
  • 2. University of Plovdiv, Bulgaria
  • 3. Karolinska Institutet,Institute for Environmental Medicine, Stockholm, Sveden,
  • 4. Institute of Molecular Biology – Bulgarian Academy of Sciences
  • 5. German Federal Institute for Risk Assessment (BfR), Berlin, germany

Description

We present experience with integrating large sets of nanosafety data generated from past NanoSafety Cluster projects with the help of a substance data model (Figure 1), implemented by the eNanoMapper database software [1]. This data model is also successfully used to handle chemical substances and safety data from ECHA dossiers [2].

•While multiple structured import formats are supported (IUCLID, RDF, JSON), the nanosafety data from past and ongoing projects use custom spreadsheet templates, currently encompassing over 1000 Excel files. Import of Excel files is enabled by a configurable parser that maps the spreadsheet data via external configuration files. Multiple export formats are supported, including tab delimited files, RDF and ISA-JSON.

•The eNanoMapper ontology[3] is used for harmonisation of the terminology and as a synonym list for query expansion.

 

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Additional details

Funding

European Commission
NanoREG II - Development and implementation of Grouping and Safe-by-Design approaches within regulatory frameworks 646221

References

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  • Jeliazkova, N.; Koch, V.; Li, Q.; Jensch, U.; Reigl, J. S.; Kreiling, R.; Georgiev, I.; Hubesch, B. Toxicol. Lett. 2016, 258, S114–S115.
  • Hastings, J.; Jeliazkova, N.; Owen, G.; Tsiliki, G.; Munteanu, C. R.; Steinbeck, C.; Willighagen, E. J. Biomed. Semantics 2015, 6 (1), 10.