FlexiDot – a customizable dotplot suite for sequence investigation and comparison
Description
This is the talk "FlexiDot – a customizable dotplot suite for sequence investigation and comparison", we gave in a regular meeting of TU Dresden's Plant Cell and Molecular Biology lab. With this talk we explain dotplots for molecular biology and introduce our FlexiDot dotplot tool.
First, we explain how a dotplot is calculated. Then, we introduce FlexiDot and compare it to other software. We explain how it works as well as its features. Subsequently, we illustrate the use of FlexiDot on a variety of examples. This includes tandem repeats (such as satellite and ribosomal DNA), transposable elements (such as LTR retrotransposons), and proteins with repeated domains (filamin proteins, nucleotide-binding leucine-rich repeat proteins).
More information on FlexiDot:
- Github: https://github.com/molbio-dresden/flexidot
- Publication: Seibt KM, Schmidt T, Heitkam T. 2018. FlexiDot: Highly customizable, ambiguity-aware dotplots for visual sequence analyses. Bioinformatics, 34: 3575–3577. https://doi.org/10.1093/bioinformatics/bty395
Files
Files
(15.3 MB)
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Additional details
Related works
- Cites
- 10.1093/bioinformatics/bty395 (DOI)
- Documents
- 10.1093/bioinformatics/bty395 (DOI)
References
- Seibt KM, Schmidt T, Heitkam T. 2018. FlexiDot: Highly customizable, ambiguity-aware dotplots for visual sequence analyses. Bioinformatics, 34: 3575–3577.