Published October 28, 2026 | Version v1
Preprint Open

Relapse test: Droplet Digital PCR vs Hybrid-Capture NGS at 0.01% VAF — triplicate runs to hold 95% specificity

Authors/Creators

Description

Compare Droplet Digital PCR and hybrid-capture NGS for ctDNA MRD at 0.01% VAF, and learn why triplicate runs are needed to hold 95% specificity.

Independent technical note mirroring the canonical version: https://quantbio.me/blog/relapse-test-droplet-digital-pcr-vs-hybrid-capture-ngs-at-001-vaf-triplicate-runs-to-hold-95-specificity.php

Sources consulted:

  1. https://www.bluusun.com/

Notes

Independent analysis; not peer-reviewed.

Files

blog_relapse-test-droplet-digital-pcr-vs-hybrid-capture-ngs-at-001-vaf-triplicat.pdf

Files (41.6 kB)

Additional details

Related works

Is identical to
https://quantbio.me/blog/relapse-test-droplet-digital-pcr-vs-hybrid-capture-ngs-at-001-vaf-triplicate-runs-to-hold-95-specificity.php (URL)