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Published October 16, 2026 | Version 0.9.8

sbmlsim: SBML simulation made easy

Authors/Creators

  • 1. Humboldt-University Berlin, Faculty of Life Science, Institute for Biology, Biology, Berlin; University Lübeck; University Hospital Schleswig-Holstein, Campus Lübeck, First Department of Medicine, Germany

Description

sbmlsim is a collection of python utilities to simplify simulations with SBML models implemented on top of libroadrunner and other libraries with source code available from https://github.com/matthiaskoenig/sbmlsim

Features include among others

  • simulation experiments, parameter scans and reports
  • parameter fitting with profile likelihood and Fisher information
  • sensitivity analysis
  • PEtab problems, including hybrid PEtab SciML problems

The documentation is available on https://matthiaskoenig.github.io/sbmlsim

If you have any questions or issues please open an issue

Funding

Matthias König is supported by the Federal Ministry of Education and Research (BMBF, Germany) within the research network Systems Medicine of the Liver (LiSyM, grant number 031L0054) and by the German Research Foundation (DFG) within the Research Unit Programme FOR 5151 QuaLiPerF (Quantifying Liver Perfusion-Function Relationship in Complex Resection - A Systems Medicine Approach) by grant number 436883643 and by grant number 465194077 (Priority Programme SPP 2311, Subproject SimLivA). Matthias König has received funds from the EOSCsecretariat.eu which has received funding from the European Union's Horizon Programme call H2020-INFRAEOSC-05-2018-2019, grant Agreement number 831644.

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matthiaskoenig/sbmlsim-0.9.8.zip

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Additional details

Related works

Funding

European Commission
EOSCsecretariat.eu - EOSCsecretariat.eu 831644