Bell's palsy: no classical HLA association and a non-MHC locus with skeletal pleiotropy

Python and R code for the genetic analysis of Bell's palsy in 5,062 Finnish cases and 431,627 controls (FinnGen release 13).

Includes: harmonisation and meta-analysis with a European dataset; SuSiE credible-set handling; MHC variant distribution and 187 imputed classical HLA alleles across eleven phenotypes; colocalisation; direct interrogation of the credible-set variants in every phenotype; the phenome-wide scan of rs9357446; cross-trait Mendelian randomisation and z-score relatedness; and the UK Biobank (Pan-UKB ICD-10 G51) replication look-up, including the GRCh37 to GRCh38 offset used to match the two datasets. All figures are drawn with base R.

Only public, de-identified summary statistics are used. No individual-level data are included or redistributed.