Published October 6, 2026 | Version v1.3.0

Nutrition_microbiome_reproducibility: reproduction of the figures of "Sugar-rich foods exacerbate antibiotic-induced microbiome disruption"

Authors/Creators

  • 1. Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA
  • 1. Institute for Systems Genetics and Department of Microbiology, NYU Langone Health Grossman School of Medicine, New York, NY, USA
  • 2. Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA
  • 3. Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA

Description

This repository facilitates reproduction of the figures from the manuscript "Sugar-rich foods exacerbate antibiotic-induced microbiome disruption", built from a small set of de-identified released tables. Every panel is rebuilt by a numbered R script that reads only from released_data/ and writes one PDF per panel.

Scripts are organised by analysis family rather than by printed figure: expensive Bayesian models are fit once and cached, then consumed by the panels that need them. The inputs needed for figure generation are available, including de-identified patient-level clinical-outcome and medication tables.

The accompanying article is published in Nature: https://doi.org/10.1038/s41586-026-11077-3. Please cite the article in preference to this software.

Files

Anqi-Dai/Nutrition_microbiome_reproducibility-v1.3.0.zip

Files (26.1 MB)

Name Size
md5:c5eebd3d6229451a9321cfac308aacfc
26.1 MB Preview Download

Additional details

Related works

Is supplement to
Journal article: 10.1038/s41586-026-11077-3 (DOI)
References
Dataset: 10.5281/zenodo.14538105 (DOI)