Published October 2, 2026
| Version v1
Dataset
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ANTI-INFLAMMATORY ACTIVITY OF AQUEOUS EXTRACTS FROM THE FRUITS OF TWO TOMATO VARIETIES CULTIVATED IN COTE DIVOIRE
Authors/Creators
- 1. 1. Training and Research Unit for Agriculture, Fisheries Resources and Agro-Industry (ARHAI), University of San Pédro (USP), 01 BP 1800 San Pédro 01, Côte d'Ivoire.
- 2. 2. Laboratory of Industrial Processes, Synthesis, Environment and New Energies (LAPISEN), National Polytechnic Institute Houphouët Boigny (INP-HB), BP 1093 Yamoussoukro, Côte d'Ivoire.
- 3. 3. Department of Sciences and Technologies, Advanced Teachers' Training College of Abidjan (ENS), 08 BP 10 Abidjan 08, Côte d'Ivoire.
- 4. 4. Laboratory of Nutrition and Food Safety (LNSA), Research Training-Unit of Sciences and Food Technologies, University Nangui Abrogoua, Abidjan, Ivory Coast.
Description
Inflammatory diseases constitute a major risk factor for the development of chronic diseases. In this context, the search of natural alternatives about treatments is essential. This study aims to evaluate the anti-inflammatory effect of extracts from two tomato varieties (Lycopersiconesculentum var. Cobra F1 and var. Locale Cotelette) cultivated in Cote d Ivoire. Anti-inflammatory activity was studied in rats (Rattus norvegicus) using a paw edema induction model, followed by treatment with the extracts. Edema evolution was monitored after administration. Hematological parameters were also analyzed to evaluate extract safety. Results showed a significant reduction in edema as early as three hours after treatment, with a more pronounced effect over time. No significant changes were observed in leukocyte and platelet counts (p > 0.05), while a slight increase in red blood cells and hemoglobin levels was recorded. These findings indicate that both tomato varieties exhibit notable anti-inflammatory activity without apparent immunotoxic effects, suggesting their potential in preventing inflammatory diseases.