Matrix Tablets as Controlled drug delivery systems

From the point of patient compliance, dosage regimen of an orally
administered drug may be considered to be optional when the therapeutic
effects are maintained for the desired duration of the treatment at the lowest
frequency of administration.The development of delivery system from
which the active substance is released at a passively controlled release rate
over an extended period of time. One of the most rational ways to increase
the therapeutic efficacy of drugs consists in creating their ready to use forms
with controlled release, which allows the desired therapeutic effects by
reduced number of drug intakes, thus decrease the level of toxicity and risk
of side effects. The modern ready-to-use medicinal forms for per oral
administration with controlled drug release include matrix tablets.