DICOM converted Slide Microscopy images for the TCGA-PCPG collection

This dataset corresponds to a collection of images and/or image-derived data available from the National Cancer Institute Imaging Data Commons (IDC). This dataset was converted into DICOM representation and ingested by the IDC team. You can explore and visualize the corresponding images using the IDC Portal. You can use the manifests included in this Zenodo record to download the collection following the Download instructions below.

Paraganglioma is a rare cancer that originates in the nerve cells of the adrenal glands, organs on top of each kidney that produce important hormones. Paraganglioma that develops in the center of the adrenal gland is called pheochromocytoma. Paraganglioma that forms outside of the adrenal gland, often along blood vessels and nerves in the head and neck, is called extra-adrenal paraganglioma, or simply paraganglioma. Each year, between 2 and 8 people per million worldwide are diagnosed with paraganglioma and pheochromocytoma. 10% of all cases occur in children. In both adults and children, pheochromocytoma is more common than paraganglioma. No known environmental, dietary, or lifestyle risk factors have been associated with these cancers.

Please see the TCGA-PCPG information page to learn more about the images and to obtain any supporting metadata for this collection.

Citation guidelines can be found on the Citing TCGA in Publications and Presentations information page.

Files included

A manifest file's name indicates the IDC data release in which a version of collection data was first introduced. For example, tcga_pcpg-idc_v22-aws.s5cmd corresponds to the contents of the tcga_pcpg collection introduced in IDC data release v22.

• tcga_pcpg-idc_v25-aws.s5cmd: AWS download manifest
• tcga_pcpg-idc_v25-gcs.s5cmd: GCS download manifest
• tcga_pcpg-idc_v25-dcf.dcf: DCF download manifest

Manifest files ending in -aws.s5cmd reference files in Amazon Web Services (AWS) buckets; -gcs.s5cmd reference files in Google Cloud Storage. The actual files are identical and mirrored between AWS and GCP.

Download instructions

Each manifest file includes instructions in its header on how to download the included files.

To download the files using .s5cmd manifests:

1. Install idc-index: pip install --upgrade idc-index
2. Download the files referenced by a manifest included in this dataset: idc download manifest.s5cmd

To download files using a .dcf manifest, see the manifest header.

For questions or help, contact support@canceridc.dev or post on the IDC Forum.

Acknowledgments

Imaging Data Commons team has been funded in whole or in part with Federal funds from the National Cancer Institute, National Institutes of Health, under Task Order No. HHSN26110071 under Contract No. HHSN261201500003I.