Published August 31, 2026 | Version v1
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SWITi Model Checkpoints: Demonstrating Tiling Artifact Attenuation with Sliding Window Inner Tiling

Description

This record contains MicroSplit model checkpoints that were used to demonstrate the attenuation of tiling artifacts when using sliding-window-inner-tiling (SWITi) in comparison to inner-tiling with a Minimum Mean Squared Error (MMSE) estimate. There are 3 sets of checkpoints that were trained on three different datasets, PaviaATN, HT-LIF24, and CBG-Z18; the training, validation and test splits are available on Zenodo. The checkpoints exhibit tiling artifacts in their predictions of the test splits. These exact checkpoints were used to report results in papers introducing the methods MicroSplit for CBG-Z18 and HT-LIF24 and scSplit for PaviaATN.

There are 3 directories, named after each dataset the models were trained on. Contained in each directory are the best and last checkpoints, BaselineVAECL_best.ckpt and BaselineVAECL_last.ckpt respectively. Additionally included is a config.yaml file containing the original training and model parameters for each set of checkpoints.
 
The checkpoints were trained with the ashesh-0/Disentangle repository. 
 

Links

Code to reproduce results in the SWITi paper is available at: https://github.com/juglab/SWITi_reproducibility.

Files

switi_checkpoints.zip

Files (370.2 MB)

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md5:b398d32b2500f8f06be23e8b1ebd1b57
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Additional details

Related works

Is derived from
Journal article: 10.1038/s41592-026-03082-1 (DOI)
Conference paper: 10.52202/085713-2160 (DOI)
Is supplement to
Preprint: 10.48550/arXiv.2607.18990 (DOI)

Funding

European Commission
IMAGINE - Next generation imaging technologies to probe structure and function of biological specimen across scales in their natural context 101094250

Software

Repository URL
https://github.com/juglab/SWITi_reproducibility
Programming language
Python
Development Status
Concept