I14. Integrated Cross-Domain Test of the Practical Value of Viability Metrology: Does a Predefined Structural Core of Vitology Retain Added Predictive and Decision Value Across Technical and Biological Systems Beyond the Strongest Domain-Specific Models?

This article formulates an integrated cross-domain architecture for testing the practical value of viability metrology.

Unlike approaches in which findings from different scientific domains are combined by simple averaging, I14 preserves differences among domains, data structures, outcome types, physical mechanisms, and levels of causal evidence.

The integrated program contains three primary test environments:

D₁ — the initial LFP/graphite technical environment.

D₂ — an independent LCO/graphite technical environment.

D₃ — the biological environment of sepsis intensive care.

For each domain, a separate strongest justified Model A_D is required.

The corresponding Vitological extension is defined as:

Model B_D = Model A_D + Φ_V,NR,D

where Φ_V,NR,D contains only prospectively defined viability information that remains after full domain-specific scientific subtraction.

I14 introduces the Domain Evidence Vector (DEV_D), the Cross-Domain Viability Evidence Matrix (CDEM_V), Structural Core Retention (SCR_V), Cross-Domain Added-Value Consistency (CAVC_V), the Cross-Domain Evidence Ceiling (CEC_V), and the Universality Gate (UG_V).

The central principle of I14 is that cross-domain support does not require identical variables, units, mechanisms, or effect sizes.

It requires preservation of the same prospectively specified structure:

Predefined Viability Structural Core

→ Non-Redundant Information

→ Improved Prediction or Decision Modification

→ More Favorable Domain-Appropriate Subsequent Evidence.

Different levels of evidence are not treated as equivalent.

Observed physical outcome gain, retrospective policy gain, predictive gain, and prospective causal confirmation remain distinct.

The strongest status available to the I11–I14 architecture without additional prospective biological intervention is defined as:

Preliminary Integrated Cross-Domain Practical Support.

This status does not establish a universal law of viability.

Keywords

Vitology; viability; cross-domain testing; evidence integration; technical systems; biological systems; lithium-ion battery; sepsis; Model A; Model B; scientific subtraction; transferability; external validity; predictive value; decision value; practical value; structural core; replication; generalization; universality.