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Published August 28, 2026 | Version 2.1.1

NeuroMetBench reproducibility package

Authors/Creators

  • 1. Independent Researcher, Amman, Jordan

Description

NeuroMetBench is a patient-aware evidence-bounding methodology for evaluating transcript-derived metabolic representations across heterogeneous proteogenomic contexts. Version 2.1.1 adds a machine-readable current article claim-evidence ledger, clarifies the cohort-conditional interpretation of BSL02 bootstrap intervals, strengthens closed-world reproducibility checks, updates the separately versioned neurometbench-ref helper software to 1.0.2 with validation-only corrections, and embeds the exact immutable v2.0.7 historical archive. Frozen article-level scientific estimates, adverse results, and claim ceilings are unchanged.

Notes

This archive is the frozen reproducibility package accompanying NeuroMetBench version 2.1.1. It contains the manuscript and supplementary-source materials, Online Resource 2, deterministic figure-generation and verification code, machine-readable claim-evidence records, software verification artifacts, provenance records, and the exact immutable NeuroMetBench v2.0.7 historical archive.

Version 2.1.1 is a corrective reproducibility and manuscript-synchronization release. It strengthens closed-world verification, hardens deterministic figure regeneration, clarifies cohort-conditional uncertainty interpretation, and updates the separately versioned neurometbench-ref helper software to version 1.0.2 with validation-only corrections. These changes do not alter the frozen article-level scientific estimates, cohort definitions, adverse findings, multiplicity families, simulation outcomes, numerical conclusions, or permitted claim ceilings.

The principal cross-modal endpoint is same-gene RNA-protein concordance and should not be interpreted as direct metabolic-flux, metabolomic, isotope-tracing, enzymatic, clinical, or universal method validation. Broad workflow calibration is not claimed.

Third-party raw molecular matrices are not redistributed where source licenses, repository policies, or access conditions govern redistribution. The MIT license applies to NeuroMetBench-authored software and documentation and does not relicense third-party datasets, dependencies, or source-study material.

Stable NeuroMetBench concept DOI: 10.5281/zenodo.21830887

Canonical v2.1.1 release archive:
NeuroMetBench_v2.1.1_reproducibility_release.zip

SHA-256:
cd809679d268674d45aa1c1e2f23de32146f0c59261b5137b5f25d7672848bef

Size:
36,623,555 bytes

Files

NeuroMetBench_v2.1.1_reproducibility_release.zip

Files (36.6 MB)

Name Size
md5:9cc50b6bc9ca509a3abae3045df3d7c5
36.6 MB Preview Download

Additional details

Related works

Is supplement to
Software: https://github.com/build33Mercury/NeuroMetBench (URL)