Analytical strategies for Simultaneous estimation of Dapagliflozin Propanediol Monohydrate, Sitagliptin Phosphate Monohydrate and Metformin Hydrochloride in Pharmaceutical Dosage Form: A Review

According to WHO,diabetes as a long-term metabolic disease characterized by elevated blood glucose levels. This could cause minor harm to the heart, kidneys, nerves, blood vessels, and eye. This review provides detail information to help researchers and analysts to select appropriate methods of analysis, quantitative by providing an idea of different analytical methods.The several analytical methods for quantitatively determining the quantities of Dapagliflozin Propanediol Monohydrate(DAPA),Sitagliptin Phosphate Monohydrate(SITA), and Metformin Hydrochloride (MET) in individual and different combination, pharmaceutical tablet dosage forms are reviewed in this article. This review focuses on the most recent measurements of three substances in pharmaceutical preparation and in bulk using spectroscopic, chromatographic, and hybrid methods. Drawbacks for each method's scope are reviewed together with its validation parameters and benefits related to regulatory difficulties. This review offers specific information to assist researchers and analysts in selecting appropriate methods for quantitative analysis.