Published August 27, 2026
| Version v0.2.1
Software
Open
Ritable: Pedigree-Based Heritability Estimation for Family Cohort Studies
Description
Provides profile-likelihood variance-components estimation of narrow-sense heritability (h2) for quantitative traits in family cohort studies. Additive genetic relationship matrices are built from pedigrees via kinship2. Phenotypes are inverse-normal transformed internally. Likelihood-ratio tests use a one-sided chi-squared boundary correction equivalent to SOLAR Eclipse. Ninety-five percent confidence intervals are derived from the profile likelihood rather than Wald approximations. Batch estimation over many traits returns tidy data frames ready for downstream visualisation.
Files
circadia-bio/R-itable-v0.2.1.zip
Files
(96.3 kB)
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md5:1e1984c70c52cf993e29b099b533fbc6
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Additional details
Related works
- Is supplement to
- Software: https://github.com/circadia-bio/R-itable (URL)
Software
- Repository URL
- https://github.com/circadia-bio/R-itable