Published August 21, 2026
| Version v1
Dataset
Open
DIFFUSE-TYPE TENOSYNOVIAL GIANT CELL TUMOR (PIGMENTED VILLONODULAR SYNOVITIS) OF THE KNEE: A CASE REPORT
Authors/Creators
- 1. 1.Sidi Mohamed Ben Abdallah University, Faculty of Medicine, Pharmacy and Dentistry, Department of Orthopedic Surgery and Traumatology A, Hassan II University Hospital, Fez, Morocco.
Description
Background:Tenosynovial giant cell tumor (TGCT), formerly known as pigmented villonodular synovitis (PVNS), is a rare, benign but locally aggressive proliferative disorder of the synovial membrane. Its diffuse type is more aggressive than the localized type and carries a substantially higher risk of recurrence. Case presentation: We report the case of a 25-year-old man with no relevant medical history who presented with mechanical pain of the right knee evolving over 4 years. Clinical examination found a mildly swollen knee, tender on palpation and mobilization, with flexion limited to 110°, full extension, mild quadriceps amyotrophy, and normal ligamentous testing, without patellar tap sign or local inflammatory signs. Standard radiographs and inflammatory markers were normal. MRI showed diffuse-type TGCT involving both compartments of the knee, without extra-articular extension.
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