Published August 10, 2026
| Version v1
Dataset
Open
Genomic drivers shape the glioblastoma microenvironment in de novo genetic mouse models and human tumours — spatial multi-omics dataset
Authors/Creators
-
1.
Deutsches Konsortium für Translationale Krebsforschung
Description
Processed spatial transcriptomic and spatial proteomic data accompanying Kastner et al. The deposit includes 10x Genomics Visium HD (n=4), 10x Genomics Xenium (n=2), and NanoString GeoMx RNA/protein data (n=12) from genetically defined murine glioblastoma models with EGFRvIII expression, Nf1 silencing, or PDGFB overexpression.
Samples:
- Visium HD: 9309A = PDGFB; 9350B = Nf1; 9248A = EGFRvIII; 9259A = EGFRvIII
- Xenium: 9233A = Nf1; 9248A = EGFRvIII
- NanoString GeoMx (sample n=12, 4 EGFRvIII expression, 4 Nf1 silencing, 4 PDGFB overexpression)
Files
Files
(4.9 GB)
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28.6 MB | Download |
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867.7 MB | Download |
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md5:d7a07787cef5e7281a159a9fc00c476f
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1.2 GB | Download |
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md5:6895dfaf5e975bc0f4b83dae1ccc201a
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860.4 MB | Download |
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md5:4c10ee66acbc299964f09566acc0f7e7
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883.8 MB | Download |
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md5:b5ab6f4a45ec200dac790f2b9ccdaadb
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374.9 MB | Download |
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md5:19769af061bad19fbe6cf326b1b4cde6
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686.7 MB | Download |