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Published August 6, 2026 | Version v1.0.2-R1

Analysis code for: A replicated astrocyte long non-coding RNA signature of Alzheimer's disease is inverted in amyotrophic lateral sclerosis

Authors/Creators

  • 1. Department of Health Pharmacy, Yokohama University of Pharmacy, Yokohama, Japan

Description

Analysis code, processed results and provenance for a donor-level, covariate-adjusted study of astrocyte long non-coding RNAs in Alzheimer's disease, amyotrophic lateral sclerosis, multiple sclerosis and major depressive disorder. The signature is defined in Alzheimer's disease alone and tested out of sample in every other cohort against a resampling null. It replicates in an independent Alzheimer's disease cohort and is inverted in two amyotrophic lateral sclerosis cohorts. Includes SHA-256 checksums of every input file, complete per-cohort differential-expression tables, and scripts reproducing every figure and table.

Files

hidenori-tani/paper-astrocyte-lncrna-atlas-v1.0.2-R1.zip

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