A Low-Cost, 3D-Printed Optomechanical Housing for a Portable 785 nm Raman Skin Probe: Design, Finite-Element Analysis, and In-Silico Validation

This repository contains a **fully parametric hardware design** and a **reproducible simulation/analysis pipeline** (CAD → FEA → optical tolerance stack-up → cost model → optional spectral classifier).

**All quantitative performance figures reported in the article and reproduced by this code are simulated / FEA-derived predictions.** The housing has **not** been physically fabricated or bench-tested; the biocompatibility and spectral-quality numbers are **in-silico model outputs calibrated to published data**, not laboratory measurements of the device. The spectral classifier is trained only on a **synthetic** dataset (no human data, `n_patients = 0`) and is a reproducible template, not a diagnostic result. See the article's *Limitations and proposed bench validation* section.

The file `data/calibration_provenance.csv` maps each simulation input parameter to the **real, citeable published source** used to calibrate it (material datasheets, SLS/MJF benchmarks, L929 MTT cytotoxicity papers, and skin-Raman band references, all with DOI/URL).