Donor-aware secondary reanalysis of GSE278330 psoriasis single-cell data

Reproducibility code for a donor-aware secondary reanalysis of the publicly available psoriasis skin single-cell RNA-sequencing dataset GSE278330. Donor identity is the sole statistical independence unit. The release contains provenance, quality-control, donor-level expression and abundance modeling, pathway analysis, residual-signal diagnostics, validation, and figure-generation scripts. Raw matrices, large derived objects, credentials, and patient-identifying data are not included.