Selection and characterization of acid-tolerant Chlorophyta division microalgae for potential metabolites production in a bubble column bioreactor: A ready-to-industrial scale screening

This publication presents a systematic screening of 28 Chlorophyta microalgal strains cultivated under standardized semi-continuous conditions in a laboratory-scale bubble column photobioreactor. The study compares biomass growth, nitrogen assimilation, and metabolite accumulation to identify strains with high industrial potential for biomass and high-value bioproduct production. Distinct physiological behaviors were identified among the investigated strains, highlighting different metabolic strategies and productivities. The proposed screening methodology provides a reproducible framework for selecting microalgal strains suitable for large-scale cultivation and contributes to bridging laboratory research and industrial microalgal bioprocess development.